Wednesday, June 16, 2010

Aluminum chloride hexahydrate

MEDICATION SAFETY ISSUES
Sound-alike/look-alike issues:
Drysol™ may be confused with Drisdol®

U.S. BRAND NAMES — Certain Dri® [OTC]; Drysol™ ; Hypercare™ ; Xerac AC™

PHARMACOLOGIC CATEGORY
Topical Skin Product

DOSING: ADULTS — Hyperhidrosis: Topical: Apply once daily at bedtime; once excessive sweating has stopped, may decrease to once or twice weekly, or as needed. Wash treated area in the morning.

DOSING: ELDERLY — Refer to adult dosing.

DOSAGE FORMS — Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution, topical:
Certain Dri®: 12% (36 mL)
Drysol™ : 20% (35 mL, 37.5 mL, 60 mL) [contains ethanol 93%]
Hypercare™ : 20% (35 mL, 37.5 mL, 60 mL) [contains ethanol 93%]
Xerac AC™ : 6.25% (35 mL, 60 mL) [contains ethanol 96%]

DOSAGE FORMS: CONCISE
Solution, topical:
Certain Dri® [OTC]: 12% (36 mL)
Drysol™ , Hypercare™ : 20% (35 mL, 37.5 mL, 60 mL)
Xerac AC™ : 6.25% (35 mL, 60 mL)

GENERIC EQUIVALENT AVAILABLE — No

ADMINISTRATION — Topical: Apply to dry skin. Area may be covered with plastic wrap held in place with snug-fitting T-shirt. Do not hold in place with tape.

USE — Astringent in the management of hyperhidrosis

ADVERSE REACTIONS SIGNIFICANT — Frequency not defined.

Dermatologic: Skin irritation

Local: Burning sensation, prickling sensation, transient itching or stinging

CONTRAINDICATIONS — Hypersensitivity to any component of the formulation

WARNINGS / PRECAUTIONS
Concerns related to adverse effects: Skin irritation: Discontinue if skin irritation occurs.

Other warnings/precautions: Appropriate use: For external use only; avoid contact with eyes. Do not apply to broken or recently shaved skin. May be harmful to certain metals or fabrics.

DRUG INTERACTIONS — There are no known significant interactions.

PRICING — (data from drugstore.com)
Solution (Drysol)
20% (35): $17.99
20% (37.5): $16.99
20% (60): $20.66

Solution (Hypercare)
20% (35): $16.99
20% (37.5): $15.99
20% (60): $18.99

Solution (Xerac AC)
6.25% (35): $16.99
6.25% (60): $18.99

INTERNATIONAL BRAND NAMES — Anhydrol Forte (GB, IE, IL); Driclor (AU, GB, HK, IE, KP, PH, SG); Drysol (CN, MX)

PATIENT INFORMATION — For external use only. Product may discolor clothing if not completely dry. Discontinue if rash develops.

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