Sunday, October 14, 2007

Vaginal hysterectomy

DEFINITION — Vaginal hysterectomy is a surgical procedure in which the uterus is removed through the vagina. One or both ovaries and fallopian tubes may be removed during the procedure, as well (show figure 1). A vaginal approach may be chosen if the uterus is not greatly enlarged, and if the condition prompting the surgery is benign and limited to the uterus. Studies have shown that vaginal hysterectomy has fewer complications, a shorter length of hospitalization, and faster recovery as compared to removal of the uterus through an abdominal incision (abdominal hysterectomy). (See "Patient information: Abdominal hysterectomy").

FEMALE ANATOMY — A brief review of female reproductive anatomy may be of help in understanding hysterectomy (show figure 2).

The uterus is a hollow, pear-shaped muscular organ located in the lower abdomen or pelvis. One end of each fallopian tube opens into the side of the uterus, at the upper end, and the other end lies next to an ovary. At its lower end, the uterus narrows and opens into the vagina. The lower end of the uterus is called the cervix. The ovaries lie next to and slightly behind the uterus.

REASONS FOR HYSTERECTOMY — A hysterectomy may be advised for a number of conditions. For some of these conditions, there may be alternatives to hysterectomy, which are described below. (See "Alternatives to hysterectomy" below).

Abnormal uterine bleeding — Excessive uterine bleeding, called menorrhagia, can lead to anemia (low blood iron count), fatigue, and contribute to missed days at work or school. Menorrhagia is generally defined as bleeding that lasts longer than seven days or saturates more than one pad per hour for several hours.

Irregular uterine bleeding, called metrorrhagia, can also occur in women with menorrhagia. Metrorrhagia is defined as bleeding or spotting that occurs at times other than during the expected menstrual period.

Menorrhagia and metrorrhagia are generally treated first with medication or other surgical alternatives to hysterectomy. (See "Patient information: Menorrhagia (Excessive menstrual bleeding)"). However, abnormal uterine bleeding that does not improve with conservative treatments may require hysterectomy.

Fibroids — Fibroids (also known as leiomyoma) are noncancerous growths of uterine muscle that occur in up to one-third of all women. Fibroids may become larger during pregnancy, and typically shrink after menopause. They may cause excessive and irregular vaginal bleeding. (See "Patient information: Fibroids").

Pelvic organ prolapse — Pelvic organ prolapse occurs due to stretching and weakening of the pelvic muscles and ligaments. This allows the uterus to fall (or prolapse) into the vagina. It is usually associated with pregnancy, vaginal childbirth, genetic factors, chronic constipation, or lifestyle factors (repeated heavy lifting over the lifetime).

Cervical abnormalities — Precancer or carcinoma in situ (CIN 3) of the cervix that does not resolve after other procedures (such as cone biopsy, laser or cryosurgery) may require hysterectomy. (See "Patient information: Screening for cervical cancer").

Endometrial hyperplasia — Endometrial hyperplasia is the term used to describe excessive growth of the endometrium (the tissue that lines the uterus). It can sometimes lead to endometrial cancer. Although endometrial hyperplasia can often be treated with medication, a hysterectomy is sometimes needed or preferred to medical therapy.

Chronic pelvic pain — Chronic pelvic pain can be due to the effects of endometriosis or scarring (adhesions) in the pelvis and between pelvic organs. However, pelvic pain can also be caused by other sources, including the gastrointestinal and urinary systems. (See "Patient information: Chronic pelvic pain in women"). It is important for a woman with pelvic pain to ask about the probability that her pain will improve after hysterectomy.

PRE-OPERATIVE PLANNING AND EVALUATION — Before surgery, there are two main decisions that need to be made: whether the ovaries should be removed, and whether estrogen replacement therapy is needed.

Removal of ovaries — A hysterectomy does not involve removing the ovaries, but they may be removed at the same time as hysterectomy; this procedure is known as oophorectomy. The decision to remove the ovaries depends upon several considerations. A list of questions to help make this decision may be found on the following table (show table 1). Occasionally, it may not be possible to remove the ovaries due to scar tissue or other factors that increase the risk of removal.

Premenopausal women may decide to keep the ovaries to provide a continued, natural source of hormones, including estrogen, progesterone, and testosterone. These hormones are important in maintaining sexual interest and preventing hot flashes and loss of bone density loss. On the other hand, women who have menstrual cycle-related migraines, epilepsy, or severe premenstrual syndrome may have an improvement in symptoms when hormone levels are reduced by removal of the ovaries. Individuals should discuss the risks and preferences with a doctor before surgery.

Postmenopausal women are usually advised to have their ovaries removed because of a small risk of developing ovarian cancer at some point during their lifetime. This benefit of removing the ovaries appears to outweigh the benefit of continued hormone production, as described above.

Estrogen replacement therapy — Estrogen replacement therapy (ERT) may be recommended after surgery for women who had their ovaries removed. Women who have not reached menopause may use ERT to avoid hot flashes, night sweats, and loss of bone density, which may occur when the ovaries are surgically removed. Women who plan to use ERT should talk with their clinician about the risks and benefits, and about how long to use this treatment.

In younger women who retain their ovaries, ERT may be needed at a later date if the ovaries stop functioning earlier than expected.

Women who have completed menopause generally do not require ERT after hysterectomy. (See "Patient information: Postmenopausal hormone therapy").

Pre-operative testing — Standard pre-operative testing may include a physical examination, EKG, chest x-ray, and blood testing, depending upon age and other medical conditions.

PROCEDURE — Vaginal hysterectomy is performed in a hospital setting, and generally requires one to two hours in the operating room. Patients are given general or spinal anesthesia plus sedation so that they feel no pain. Heart rate, blood pressure, blood loss, and respiration are closely observed throughout the procedure. After surgery, patients are transferred to the recovery room (also known as the post-anesthesia care unit) so that they can be monitored while waking up. Most patients will then be transferred to a hospital room and will stay one to two days.

LAPAROSCOPICALLY ASSISTED VAGINAL HYSTERECTOMY (LAVH) — Laparoscopically assisted vaginal hysterectomy (LAVH) is done by some surgeons to assist with the vaginal hysterectomy procedure. A laparoscope is a surgical instrument inserted through a small incision in the abdomen and pelvis. Using the scope, the surgeon can more easily see the uterus, ovaries, and the tissues that surround these organs within the pelvis (show figure 3).

In addition, instruments may be used, along with the laparoscope, to facilitate the removal of the uterus through the vagina. LAVH might be recommended for a woman with an enlarged uterus, history of prior pelvic surgery, endometriosis, or other factors that could complicate a traditional vaginal hysterectomy. Women generally recover faster after a vaginal hysterectomy or LAVH, as compared to women who have abdominal hysterectomy.

However, not all surgeons use laparoscopy since additional training, experience, and equipment is necessary. Patients should talk to their surgeon regarding the best procedure for their individual situation.

NEED FOR ABDOMINAL HYSTERECTOMY — After surgery has begun, the surgeon may find conditions, such as extensive scar tissue, that require him or her to make an abdominal incision to remove the uterus. Sometimes these conditions are not apparent before surgery.

COMPLICATIONS — A number of complications can occur as a result of hysterectomy. Fortunately, most can be easily managed and do not cause long-term problems.

Hemorrhage — Excessive bleeding (hemorrhage) occurs in a small number of cases. Excessive bleeding may require a blood transfusion and/or a return to the operating room to find and stop it.

Infection — Low-grade fever is common after hysterectomy, is not always caused by infection, and usually resolves without treatment. However, a high or persistent fever may signal an infection. Serious infection occurs in less than five percent of women, and can usually be treated with intravenous antibiotics. Much less commonly, patients require another surgical procedure.

Constipation — Constipation occurs in most women following hysterectomy, and can usually be controlled with a regimen of stool softeners, dietary fiber, and laxatives.

Urinary retention — Urinary retention, or the inability to pass urine, can occur after vaginal hysterectomy. Urine can be drained using a catheter until retention resolves, usually within 24 to 48 hours.

Blood clots — Pelvic surgery increases the risk of developing blood clots in the large veins of the leg or lung. The risk is increased for approximately six weeks after surgery. Medications may be given to some women to prevent blood clots. In addition, women taking oral contraceptives or hormone replacement should ideally discontinue them one month prior to surgery since they can further increase the risk of blood clots. Women who are sexually active and premenopausal should use alternative methods of birth control (e.g. condoms) to prevent pregnancy before surgery. (See "Patient information: Venous thrombosis").

Damage to adjacent organs — The urinary bladder, ureters (small tubes leading from the kidneys to the bladder), and large and small intestines are located in the lower abdomen and pelvis and can be injured during hysterectomy. Bladder injury occurs one to two percent of women who have vaginal hysterectomy, while bowel injury occurs in less than one percent of women. Injury can usually be detected and corrected at the time of surgery. If detected after surgery, another operation may be needed.

Early menopause — Women who have undergone hysterectomy may experience menopause earlier than the average age of menopause (age 51). This may be due to an interruption in blood flow to the ovaries as a result of removing the uterus.

RECOVERY AFTER SURGERY — Fluids and food are generally offered soon after surgery. Intravenous (IV) fluids may be administered during the first day, particularly if there is nausea or vomiting. Pain medicine is given as needed, either intravenously, or by intramuscular (IM) injection or pill. Patients are encouraged to resume their normal daily activities as soon as possible. Regaining mobility is particularly important since it helps to prevent complications, such as blood clots, pneumonia, and gas pains.

Walking and stair climbing are encouraged; tub baths and showers are permitted. Driving should be avoided until full mobility returns and narcotic pain relievers are no longer required.

To minimize stress on the healing tissues, patients will be asked to avoid lifting greater than 20 pounds (9 kg) for four to six weeks after surgery. Vaginal intercourse, tampons, and douching are not recommended for the same time period to allow complete healing.

A patient should call her surgeon if she experiences pain that is not relieved with medication, persistent nausea or vomiting, bleeding heavier than a menstrual period, fever greater than 101º F or 38º C, foul-smelling vaginal discharge, or inability to empty the bladder or bowels.

Constipation is common after surgery and while using narcotic pain medications, and can often be controlled with stool-softening medications such as Colace® (docusate sodium) and stool bulking agents such as psyllium (Metamucil®), methylcellulose (Citrucel®), or calcium polycarbophil (FiberCon®). (See "Patient information: Constipation in adults"). A woman who does not have a bowel movement within 3 days should contact her surgeon for further advice.

Normal activities can be resumed gradually over a six-week period. Patients may return to work as soon as they have sufficient stamina and mobility.

LIFE AFTER HYSTERECTOMY — Studies of women's response to hysterectomy show that most women are very satisfied with their results (show table 2). Most reported improvement in symptoms directly related to the uterus, including pain and vaginal bleeding.

Sexual function and enjoyment, interest in sex, and pain with sex were improved for most women. However, this improvement may be dependent upon several factors, including the age of a woman at the time of surgery, the reason for surgery, and history of any prior difficulties with mood. Younger women may grieve after hysterectomy due to their loss of fertility. A woman who has new feelings of sadness, anxiety, or depression after surgery should speak with her healthcare provider. These feelings may be treated by talking with a therapist, with antidepressant medication, or may resolve with time.

ALTERNATIVES TO HYSTERECTOMY — Some women who wish to avoid or postpone hysterectomy may use medications or less invasive surgical procedures. Medical and surgical alternatives to hysterectomy depend upon the underlying disorder. The decision as to which treatment is "best" should be based upon a woman's particular medical problem, all available treatment options, and the risks and benefits of each type of treatment.

Some alternatives to vaginal hysterectomy include the following: Uterine artery embolization and myomectomy may be used to treat symptomatic leiomyoma (fibroids). (See "Patient information: Fibroids"). Pain clinics may be able to treat patients with severe and chronic pelvic pain without surgery. (See "Patient information: Chronic pelvic pain in women"). Endometrial ablation, in which a physician destroys or removes most of the endometrium using an instrument inserted through the vagina and cervix and into the uterus. (See "Patient information: Menorrhagia (Excessive menstrual bleeding)"). Medical therapy using hormonal medications, such GnRH analogs (for example, leuprolide) or progestins can help reduce the pain associated with endometriosis. (See "Patient information: Endometriosis"). Cone biopsy (eg, cold knife cone), cryosurgery, laser surgery, or loop electrocautery (eg, LEEP or LLETZ) are usually used to treat women with high-grade cervical intraepithelial neoplasia or carcinoma in situ of the cervix. These procedures remove the abnormal part of the cervix rather than the entire cervix and uterus (See "Patient information: Screening for cervical cancer").

WHERE TO GET MORE INFORMATION — Your healthcare provider is the best source of information for questions and concerns related to your medical problem. Because no two patients are exactly alike and recommendations can vary from one person to another, it is important to seek guidance from a provider who is familiar with your individual situation.

This discussion will be updated as needed every four months on our web site (www.patients.uptodate.com). Additional topics as well as selected discussions written for healthcare professionals are also available for those who would like more detailed information.

A number of web sites have information about medical problems and treatments, although it can be difficult to know which sites are reputable. Information provided by the National Institutes of Health, national medical societies and some other well-established organizations are often reliable sources of information, although the frequency with which they are updated is variable. National Library of Medicine

(www.nlm.nih.gov/medlineplus/healthtopics.html)
The American College of Obstetricians and Gynecologists

(www.acog.org)
U.S. Department of Health & Human Services, Federal Government Source for Women's Health Information

(www.4woman.gov)


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Use of UpToDate is subject to the Subscription and License Agreement. REFERENCES 1. Meeks, GR, Harris, RL. Surgical approach to hysterectomy: Abdominal, Laparoscopy-assisted, or vaginal. Clin Obstet Gynecol 1997; 40:886.
2. Harris, WJ. Complications of hysterectomy. Clin Obstet Gynecol 1997; 40:928.
3. Carlson, KJ, Miller, BA, Fowler, FJ, Jr. the Maine Women's Health Study I: Outcomes of hysterectomy. Obstet Gynecol 1994; 83:556.
4. Rhodes, JC, Kjerulff, KH, Langenberg, PW, Guzinski, GM. Hysterectomy and sexual functioning. JAMA 1999; 282:1934.

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